How many women need a non-hormonal contraceptive like this?

The global contraceptive market has been estimated to exceed $20 billion annually. Yaso addresses the unmet demand for non-hormonal, discreet, dual-purpose products — positioning us as a potential category leader. Yaso is delivering proven science to solve women’s most urgent family planning needs.

Aren’t some vaginal gels messy?

Not Yaso. Older products had residue or stickiness, but Yaso Gel was designed differently. It’s clean, aqueous, quick-drying, and discreet — more like a modern skincare product than a traditional gel. We are advancing the next generation of reproductive health.

How long does it work in the vagina?

Preclinical data show Yaso provides protection for several hours. Ongoing studies are confirming duration and real-world use so women can rely on it with confidence.

What is the efficacy target with typical use?

Typical use is affected by user adherence to the method in insertion. In several published studies it is not unusual to find when any new method is introduced, efficacy can initially appear lower than targeted, but over time, efficacy improves with regular use, which is typical with virtually any new product. We formulated Yaso Gel to be as pleasant to use as an aqueous personal lubricant to encourage regular and correct use of the vaginal contraceptive. We used the male condom as a widely-known performance benchmark, because not only is it contraceptive, but prevents STD infections: a potential benefit in Yaso Gel but not competitors.

Do some current gels cause irritation?

Yes, older products often did. Yaso’s formula is designed to be gentle and well-tolerated. Early safety testing shows promising results, and women in trials will report their experiences directly.

Will women be able to buy it over the counter (OTC)?

That’s our goal. We want women to access Yaso without barriers. The final decision depends on FDA review and regulatory approval, but OTC access is part of our mission. If a investor/partner elected to go Rx first, they would influence that strategy. In fact, there may be options for various product formulations. Conceivably, the FDA may require some period of time as an Rx, since PPCM is a new chemical entity. We are making possible a world where family planning is an easy choice, not a privilege.

How will the price compare?

Final pricing will be set closer to launch. Yaso is being developed to be cost-effective — less expensive than many prescription contraceptives and more practical than complex biologics. We are breaking down barriers to safe and affordable contraception.

What do doctors think?

Women’s health experts and general practitioners have responded positively. Physicians recognize the need for non-hormonal, discreet options. Yaso also stands out for its potential dual use — contraception plus broad infection protection. Plus, antibiotic-resistant strains of gonorrhea are a threat today.

What is the regulatory pathway?

We are pursuing FDA approval beginning with Phase 1 trials. The long-term goal is over-the-counter (OTC) availability, which could make Yaso Gel a first-in-class, globally accessible contraceptive and protective product. We are grounding bold innovation in FDA-reviewed science.

How does Yaso Gel compare to other technologies?

Unlike monoclonal antibodies or complex biologics, Yaso’s gel is simple, stable, and cost-effective to manufacture. This enables rapid global scalability and affordability. In women’s health, safety, formulation, and delivery matter more than “molecular fashion.” A proven class de-risks the development program. Yaso Gel with PPCM is much closer to real-world application in contraception. We are setting the benchmark for non-hormonal contraception worldwide.