Our extensive market surveys revealed high interest among:
- women who don’t like, don’t trust, or can’t use hormones and/or find surfactants irritating,
- women who have children, and want to delay having another child right now
- women who may not be in a permanent relationship, and who do not want children or marriage at this time.
- women who are concerned about STIs and securing regular use of condoms by their male partner.
Our non-hormonal, on-demand vaginal gel protects against unplanned pregnancy and STIs.
The contraceptive market was $17 billion, at retail, in 2015. Revenues are generated primarily from hormonal products, the copper IUD and condoms. Over 3 million American women experience unplanned pregnancy every year. Globally, there are 84 million unplanned pregnancies globally every year.
Many women still do not have access to birth control products because they lack insurance, can’t afford them or they may not be in a committed relationship that justifies the cost and side effects of daily hormonal contraceptives. There is also high interest in non-hormonal contraceptives because many women dislike side effects and remain concerned about their long-term health. OTC contraceptives are, in theory, available but are all based on nonoxynol-9, an irritating surfactant that promotes infection in women.
Sexually Transmitted Infections
Case Study: Genital Herpes
Herpes simplex virus infection is incurable. 16% of all American adults have genital herpes, many of whom have recurrent outbreaks of herpes lesions. Recurrent genital lesions are primarily caused by HSV-2 and it is a serious source of morbidity and mortality, and a co-factor in HIV infection. The incidence and prevalence of genital herpes in the US is growing. The CDC estimates 63 million Americans have HSV-2. There will be an estimated 500,000 to 1,000,000 new infections annually in the US alone.
Worldwide, more than 600 million people have genital herpes. In some countries, prevalence exceeds 50%.
Our active drug, PPCM, can prevent cell-to-cell spread of herpes virus. This is important because PPCM topical gel may be useful in stopping an outbreak of herpes lesions if applied early in the outbreak. And, PPCM topical gel, if used properly during sexual intercourse, could prevent infection between individuals.